Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | NCI_SYNDECAN-4-MEDIATED SIGNALING EVENTS |
| Enrichment Score (ES) | -0.65268326 |
| Normalized Enrichment Score (NES) | -1.656852 |
| Nominal p-value | 0.0053956835 |
| FDR q-value | 0.2812692 |
| FWER p-Value | 0.653 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DNM2 | 50176 3170279 | 944 | 0.985 | -0.0158 | No | ||
| 2 | MAP3K7IP1 | 2120095 5890452 6040167 | 1119 | 0.889 | 0.0065 | No | ||
| 3 | CDC42 | 1240168 3440278 4480519 5290162 | 1613 | 0.666 | 0.0036 | No | ||
| 4 | GIPC1 | 4590348 5570438 5900707 | 2204 | 0.471 | -0.0114 | No | ||
| 5 | PRKCA | 6400551 | 2259 | 0.456 | 0.0019 | No | ||
| 6 | TNFRSF13B | 1990373 | 2789 | 0.325 | -0.0150 | No | ||
| 7 | RHOA | 580142 5900131 5340450 | 3010 | 0.287 | -0.0166 | No | ||
| 8 | WNT5A | 840685 3120152 | 3512 | 0.211 | -0.0361 | No | ||
| 9 | MDK | 3840020 | 4036 | 0.158 | -0.0586 | No | ||
| 10 | F2 | 5720280 | 4430 | 0.127 | -0.0752 | No | ||
| 11 | CXCL12 | 580546 4150750 4570068 | 4549 | 0.120 | -0.0773 | No | ||
| 12 | NFATC2 | 70450 540097 | 4572 | 0.118 | -0.0743 | No | ||
| 13 | THBS1 | 4560494 430288 | 4657 | 0.114 | -0.0748 | No | ||
| 14 | FN1 | 1170601 2970647 6220288 6940037 | 4923 | 0.099 | -0.0856 | No | ||
| 15 | WNT11 | 1230278 | 5344 | 0.080 | -0.1053 | No | ||
| 16 | FGF2 | 3450433 | 6098 | 0.055 | -0.1439 | No | ||
| 17 | YES1 | 6100050 | 6574 | 0.044 | -0.1679 | No | ||
| 18 | LAMA1 | 1770594 | 7946 | 0.019 | -0.2411 | No | ||
| 19 | LAMA3 | 1190131 5290239 | 7956 | 0.019 | -0.2409 | No | ||
| 20 | FZD6 | 360288 | 9549 | -0.004 | -0.3265 | No | ||
| 21 | PLG | 3360270 3840100 | 10651 | -0.020 | -0.3851 | No | ||
| 22 | NLK | 2030010 2450041 | 10808 | -0.022 | -0.3927 | No | ||
| 23 | WNT4 | 4150619 | 11291 | -0.030 | -0.4175 | No | ||
| 24 | CAMK2A | 1740333 1940112 4150292 | 12157 | -0.047 | -0.4624 | No | ||
| 25 | ITGA5 | 5550520 | 12796 | -0.064 | -0.4945 | No | ||
| 26 | SDCBP | 460487 2190039 5270441 | 13100 | -0.073 | -0.5082 | No | ||
| 27 | PRKCD | 770592 | 13430 | -0.086 | -0.5229 | No | ||
| 28 | MAP3K7 | 6040068 | 13743 | -0.099 | -0.5362 | No | ||
| 29 | FZD3 | 1500397 | 13888 | -0.106 | -0.5402 | No | ||
| 30 | CSNK1A1 | 2340427 | 14110 | -0.119 | -0.5478 | No | ||
| 31 | TNC | 670053 1780039 1980020 3060411 4780091 6860433 | 14184 | -0.125 | -0.5473 | No | ||
| 32 | PLCG1 | 6020369 | 14633 | -0.160 | -0.5657 | No | ||
| 33 | FZD7 | 7050706 | 14839 | -0.178 | -0.5705 | No | ||
| 34 | FGFR1 | 2190095 4570161 | 14921 | -0.189 | -0.5681 | No | ||
| 35 | ADAM12 | 3390132 4070347 | 15196 | -0.224 | -0.5749 | No | ||
| 36 | MMP9 | 580338 | 15644 | -0.298 | -0.5883 | No | ||
| 37 | TFPI | 1400288 5550008 | 16840 | -0.652 | -0.6295 | Yes | ||
| 38 | WNT6 | 4570364 | 17005 | -0.723 | -0.6126 | Yes | ||
| 39 | RAC1 | 4810687 | 17179 | -0.806 | -0.5933 | Yes | ||
| 40 | GNAS | 630441 1850373 4050152 | 17542 | -0.997 | -0.5773 | Yes | ||
| 41 | GNB1 | 2120397 | 18190 | -1.508 | -0.5585 | Yes | ||
| 42 | GNG2 | 2230390 | 18284 | -1.627 | -0.5056 | Yes | ||
| 43 | CCL5 | 3710397 | 18574 | -2.710 | -0.4248 | Yes | ||
| 44 | ITGB1 | 5080156 6270528 | 18580 | -2.818 | -0.3248 | Yes | ||
| 45 | PTK2 | 1780148 | 18588 | -3.004 | -0.2183 | Yes | ||
| 46 | SDC4 | 6370411 | 18590 | -3.068 | -0.1092 | Yes | ||
| 47 | CXCR4 | 4590519 | 18594 | -3.106 | 0.0012 | Yes |
